Workflows and Procedures for Cannabis Testing and Analysis

Cannabinoid analysis in Hemp and Cannabis by HPLC-UV

Many countries throughout the world have started to legalize hemp and cannabis. In the United States, testing cannabis and hemp for compliance is required. As a result, robust and accurate analytical methods are essential for meeting the regulatory requirements for THC content. Beyond THC, there is emerging interest in the therapeutic benefits of minor cannabinoids. This has increased the demand for high resolution methods capable of separating the diverse and expanding list of cannabinoids.

A complete HPLC workflow has been developed to simplify cannabinoid profiling and potency determination. This workflow offers the following:

  • Step-by-step instructions for sample preparation and analysis of 17 cannabinoids
  • Rapid High-Resolution Gradient Method: 6 minutes on C18 column (2 µm)
  • Rapid Gradient Method: 6 minutes on C18 (2.7 µm)
  • Low Pressure Isocratic Method: 8 minutes on C8 column (2.7 µm)
  • Low flow rate for reduced solvent consumption
  • Compatibility with mass spectrometry

Heavy metal testing in cannabis

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Pesticide analysis in Hemp and Cannabis by LC-MS/MS and GC-MS/MS

Recreational cannabis use has been legalized in 11 states and the District of Columbia with an additional 22 allowing use of medical marijuana. ​

Growers and processors of cannabis and its derivative products must show their products to be safe according to individual state requirements. Generally requirements include testing to ensure that the cannabis flower is free of pesticides.​

As your partner in analytical testing, we've made a step-by-step guide to pesticide analysis available for your cannabis workflow.  We provide sample prep consumables, standards for calibration, columns, consumables and solvents for instrument analysis and a comprehensive application to obtain consistent results.  The application includes a common procedure for preparation of standards and extraction of plant material followed by splitting into GC-MS/MS and LC-MS/MS with a focus on the California list of pesticides.

In addition, you can also find all the Pipettes, Pipettors and Tips that you need for accurate GC and LC analysis of hemp and cannabis products.  

Milli-Q® ultrapure water purification systems,  LiChroSolv® solvents for liquid chromatography  and SupraSolv® solvents for gas chromatography provide superior quality for the most demanding applications.

 

Heavy metal analysis in Hemp and Cannabis by ICP-MS

Heavy metals such as iron, cobalt or molybdenum are nutritionally essential for humans, animals and plants. In contrast, higher concentrations of the former and of metals like lead, mercury or cadmium are toxic to organisms. These heavy metals can accumulate in plants by uptake from soil or water so heavy metal testing of unprocessed and processed plants is necessary.

Heavy metal content in Cannabis is regulated in many countries. In the USA, over 20 states have issued regulations as of January 2020. All of them provide limits for arsenic, cadmium, mercury and lead (referred to as the “big four”). In addition, four states set limits for one or more of these metals: chromium, barium, silver, selenium, antimony, copper, nickel and zinc.1-3

As your partner in analytical testing, we've made step-by-step guides to heavy metals analysis available for each part of your ICP-MS workflow.

Heavy metal testing in cannabis

In addition, you can also find all the Pipettes, Pipettors, Tips and Centrifuge Tubes that you need for accurate ICP analysis of hemp and Cannabis products.

Milli-Q® ultrapure water purification systems and Ultrapur bottled water provide superior quality for the most demanding applications.

 

Applications