Customer Education

Webinar: Tapping the Potential of Gene Editing Technology to Improve Cell-Based Assays for ADME/Tox

Date: Tuesday, April 30, 2019

Time: 12:00 PM (CST)

Duration: 60 minutes

Presenter: David C. Thompson, Ph.D.

 What Does it Cover?

Advances in gene editing technologies have generated a great amount of interest within the scientific community over the past few years.  In addition to the ability to make precise double stranded DNA cuts virtually anywhere in the human genome, new variations of these tools show promise in the ability to activate or repress the expression of individual genes. Besides the obvious interest in clinical applications for these tools, there are practical uses of these tools for modifying and improving in vitro cell-based assays in areas such as preclinical ADME/Tox.  This webinar will highlight these recent advances in gene editing technology and provide several examples of how this technology has been applied to ADME/Tox assays, including intestinal, hepatic and renal proximal tubule cell lines.

 What Will You Learn?

  • Review recent advances in gene editing technology to modify the activity of genes of interest
  • Learn about various applications of this technology to the ADME/Tox field
  • Hear specific examples of drug transporter knockout/knockin cell lines

 Who Should Attend?

  • Academic researchers
  • Pharma researchers
  • ADME scientists
  • DMPK scientists
  • Toxicology scientists
  • Drug discovery scientists

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