Good’s Buffers
"Good′s" Buffers refer to the group of buffers described in the research of Dr. Norman Good et al. in 1966. These buffers were selected because they display characteristics making them integral to research in biology and biochemistry. The characteristics associated with a Good′s buffer include the following: pKa value between 6.0 and 8.0, high solubility, non toxic, limited effect on biochemical reactions, very low absorbence between 240 nm and 700 nm, enzymatic and hydrolytic stability, minimal changes due to temperature and concentration, limited effects due to ionic or salt composition of the solution, limited interaction with mineral cations, and limited permeability of biological membranes. (Reference: Good, N.E., et al. (1966) Hydrogen Ion Buffers for Biological Research. Biochemistry 5(2), 467-477.)

For additional technical details, visit the Buffer Reference Center.

Product #

Description

Useful pH Range

CAS Number

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GB11 “Good” buffers      
    • A9758 ACES ≥99.0% (titration) 6.1 - 7.5
    		 7365-82-4 6.8
    • A3594 ACES BioPerformance Certified, ≥99.0%, suitable for cell culture 6.1 - 7.5
    		 7365-82-4 6.8
    • A7949 ACES BioXtra, ≥99.0% (titration) 6.1 - 7.5
    		 7365-82-4 6.8
    • RES1000A-A7 ACES PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 6.1 - 7.5
    		 7365-82-4 6.8
    • A0153 ADA disodium salt 6.0 - 7.2
    		 41689-31-0 6.6
    • A9883 ADA ≥98% (titration) 6.0 - 7.2
    		 26239-55-4 6.6
    • B2891 BES sodium salt ≥99% (titration) 6.4 - 7.8
    		 66992-27-6 7.1
    • B9879 BES ≥99.0% (titration) 6.4 - 7.8
    		 10191-18-1 7.1
    • B4554 BES BioPerformance Certified, suitable for cell culture, ≥99.0% 6.4 - 7.8
    		 10191-18-1 7.1
    • B6420 BES BioXtra, ≥99.0% (titration) 6.4 - 7.8
    		 10191-18-1 7.1
    • B3876 BICINE ≥99% (titration) 7.6 - 9.0
    		 150-25-4 8.3
    • B8660 BICINE BioXtra, ≥99% (titration) 7.6 - 9.0
    		 150-25-4 8.3
    • B6032 BIS-TRIS hydrochloride ≥99.0% (titration) 5.8 - 7.2
    		 124763-51-5 6.5
    • RES1164B-A7 BIS-TRIS hydrochloride PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production., suitable for cell culture 5.8 - 7.2
    		 124763-51-5 6.5
    • B6755 BIS-TRIS propane ≥99.0% (titration) 6.3 - 9.5
    		 64431-96-5 6.8
    • B4679 BIS-TRIS propane BioPerformance Certified, suitable for cell culture, ≥99.0% 6.3 - 9.5
    		 64431-96-5 6.8
    • B9410 BIS-TRIS propane BioXtra, ≥99.0% (titration) 6.3 - 9.5
    		 64431-96-5 6.8
    • PHG0005 BIS-TRIS propane PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 6.3 - 9.5
    		 64431-96-5 6.8
    • B9754 BIS-TRIS ≥98.0% (titration) 5.8 - 7.2
    		 6976-37-0 6.5
    • B4429 BIS-TRIS BioPerformance Certified, suitable for cell culture, suitable for insect cell culture, ≥98.0% 5.8 - 7.2
    		 6976-37-0 6.5
    • B7535 BIS-TRIS BioXtra, ≥98.0% (titration) 5.8 - 7.2
    		 6976-37-0 6.5
    • PHG0004 BIS-TRIS PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 5.8 - 7.2
    		 6976-37-0 6.5
    • RES1161B-A7 BIS-TRIS PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production., suitable for cell culture 5.8 - 7.2
    		 6976-37-0 6.5
    • RES1151B-B7 Bicine PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production., suitable for cell culture 7.6 - 9.0
    		 150-25-4 8.3
    • C2632 CAPS ≥99%   1135-40-6 10.4
    • C6070 CAPS BioXtra, ≥99%   1135-40-6 10.4
    • C2154 CAPSO sodium salt 8.9 - 10.3
    		 102601-34-3 9.6
    • C2278 CAPSO ≥99% anhydrous basis (titration) 8.9 - 10.3
    		 73463-39-5 9.6
    • C2885 CHES ≥99.0% (titration) 8.6 - 10.0
    		 103-47-9 9.3
    • C8210 CHES BioXtra, ≥99.0% (titration) 8.6 - 10.0
    		 103-47-9 9.3
    • RES1299C-B7 CHES PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production., suitable for cell culture 8.6 - 10.0
    		 103-47-9 9.3
    • D0306 DIPSO BioXtra, pH 4.0-5.5 (20 °C, 0.1 M in H2O), ≥98% (titration) 7.0 - 8.2
    		 68399-80-4 7.6
    • E9502 EPPS ≥99.5% (titration) 7.3 - 8.7
    		 16052-06-5 8
    • E0276 EPPS BioPerformance Certified, suitable for cell culture, ≥99.5% (titration) 7.3 - 8.7
    		 16052-06-5 8
    • E1894 EPPS BioXtra, ≥99.5% (titration) 7.3 - 8.7
    		 16052-06-5 8
    • G1002 Gly-Gly ≥99% (titration) 7.5 - 8.9
    		 556-50-3 8.2
    • G3915 Gly-Gly BioPerformance Certified, suitable for cell culture, ≥99% 7.5 - 8.9
    		 556-50-3 8.2
    • H6903 HEPBS ≥99% (titration) 7.6 - 9.0
    		 161308-36-7 8.3
    • H7637 HEPES hemisodium salt ≥99% (titration) 6.8 - 8.2
    		 103404-87-1 7.5
    • H9897 HEPES hemisodium salt dry powder 6.8 - 8.2
    		 103404-87-1 7.5
    • H0527 HEPES potassium salt ≥99.5% (titration) 6.8 - 8.2
    		 82207-62-3 7.5
    • H2393 HEPES sodium salt hydrate ≥99% (titration) 6.8 - 8.2
    		 75277-39-3 7.5
    • H3662 HEPES sodium salt solution 1M, BioReagent, suitable for cell culture   75277-39-3  
    • H7006 HEPES sodium salt ≥99.5% (titration) 6.8 - 8.2
    		 75277-39-3 7.5
    • H3784 HEPES sodium salt BioPerformance Certified, suitable for cell culture, ≥99.5% 6.8 - 8.2
    		 75277-39-3 7.5
    • H8651 HEPES sodium salt BioXtra, ≥99.0% (titration) 6.8 - 8.2
    		 75277-39-3 7.5
    • RES6007H-A7 HEPES sodium salt PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 6.8 - 8.2
    		 75277-39-3 7.5
    • H3537 HEPES solution BioPerformance Certified, 1 M, suitable for cell culture, 0.2 μm filtered 6.8 - 8.2
    		 7365-45-9  
    • H3375 HEPES ≥99.5% (titration) 6.8 - 8.2
    		 7365-45-9 7.5
    • RES6008H-A7 HEPES, Hemisodium Salt PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 6.8 - 8.2
    		 103404-87-1 7.5
    • H4034 HEPES BioPerformance Certified, ≥99.5% (titration), suitable for cell culture 6.8 - 8.2
    		 7365-45-9 7.5
    • H7523 HEPES BioXtra, pH 5.0-6.5 (1 M in H2O), ≥99.5% (titration) 6.8 - 8.2
    		 7365-45-9 7.5
    • PHG0001 HEPES PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 6.8 - 8.2
    		 7365-45-9 7.5
    • RES6003H-B7 HEPES PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 6.8 - 8.2
    		 7365-45-9 7.5
    • M8902 MES hemisodium salt ≥98% (titration) 5.5 - 6.7
    		 117961-21-4 6.1
    • M0164 MES hemisodium salt dry powder 5.5 - 6.7
    		 117961-21-4 6.1
    • M8250 MES hydrate ≥99.5% (titration) 5.5 - 6.7
    		 1266615-59-1 6.1
    • M5287 MES hydrate ≥99.5% (titration), pH 2.5-4.0 (0.5 M in H2O), BioXtra 5.5 - 6.7
    		 1266615-59-1 6.1
    • M2933 MES hydrate BioPerformance Certified, suitable for cell culture, ≥99.5% 5.5 - 6.7
    		 1266615-59-1 6.1
    • PHG0003 MES hydrate PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 5.5 - 6.7
    		 1266615-59-1 6.1
    • RES0113M-A7 MES monohydrate PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 5.5 - 6.7
    		 145224-94-8 6.1
    • M0895 MES potassium salt ≥99% (titration) 5.5 - 6.7
    		 39946-25-3 6.1
    • M3885 MES sodium salt ≥99% (titration) 5.5 - 6.7
    		 71119-23-8 6.1
    • M3058 MES sodium salt BioPerformance Certified, suitable for cell culture 5.5 - 6.7
    		 71119-23-8 6.1
    • M5057 MES sodium salt BioReagent, ≥99% (titration), crystalline 5.5 - 6.7
    		 71119-23-8 6.1
    • PHG0008 MES sodium salt PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 5.5 - 6.7
    		 71119-23-8 6.1
    • RES0114M-A7 MES sodium salt PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 5.5 - 6.7
    		 71119-23-8 6.1
    • M1317 MES solution suitable for, BioPerformance Certified, 1 M, suitable for cell culture 5.5 - 6.7
    		    
    • M3671 MES low moisture content, ≥99% (titration) 5.5 - 6.7
    		 4432-31-9 6.1
    • M3295 MOBS ≥99% (titration) 6.9 - 8.3
    		 115724-21-5 7.6
    • M9027 MOPS hemisodium salt ≥99% (titration) 6.5 - 7.9
    		 117961-20-3 7.2
    • M0289 MOPS hemisodium salt foil pouch 6.5 - 7.9
    		 117961-20-3 7.2
    • M9381 MOPS sodium salt ≥99.5% (titration) 6.5 - 7.9
    		 71119-22-7 7.2
    • M9024 MOPS sodium salt BioPerformance Certified, suitable for cell culture, ≥99.5% 6.5 - 7.9
    		 71119-22-7 7.2
    • M5789 MOPS sodium salt BioXtra, ≥99.5% anhydrous basis (titration) 6.5 - 7.9
    		 71119-22-7 7.2
    • RES0197M-A7 MOPS sodium salt PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 6.5 - 7.9
    		 71119-22-7 7.2
    • M1442 MOPS solution BioPerformance Certified, 1 M, suitable for cell culture 6.5 - 7.9
    		    
    • M1254 MOPS ≥99.5% (titration) 6.5 - 7.9
    		 1132-61-2 7.2
    • M3183 MOPS BioPerformance Certified, suitable for cell culture, ≥99.5% (titration) 6.5 - 7.9
    		 1132-61-2 7.2
    • M5162 MOPS BioXtra, ≥99.5% (titration) 6.5 - 7.9
    		 1132-61-2 7.2
    • M8767 MOPSO sodium salt ≥99% (titration) 6.2 - 7.6
    		 79803-73-9 6.9
    • M5914 MOPSO sodium salt BioXtra, pH 10-12 (1 M in H2O), ≥99% (titration) 6.2 - 7.6
    		 79803-73-9 6.9
    • M8389 MOPSO ≥99% (titration) 6.2 - 7.6
    		 68399-77-9 6.9
    • RES0199M-A7 MOPSO, sodium salt PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 6.2 - 7.6
    		 79803-73-9 6.9
    • RES0196M-B7 MOPSO PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 6.2 - 7.6
    		 68399-77-9 6.9
    • PHG0007 MOPS PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 6.5 - 7.9
    		 1132-61-2 7.2
    • P7643 PIPES dipotassium salt ≥99% (titration) 6.1 - 7.5
    		 108321-27-3 6.8
    • P3768 PIPES disodium salt ≥99% (titration) 6.1 - 7.5
    		 76836-02-7 6.8
    • P8655 PIPES sesquisodium salt ≥99% (titration) 6.1 - 7.5
    		 100037-69-2 6.8
    • P2949 PIPES sodium salt ≥99% (titration) 6.1 - 7.5
    		 10010-67-0 6.8
    • P6757 PIPES ≥99% (titration) 6.1 - 7.5
    		 5625-37-6 6.8
    • RES0704P-A7 PIPES, disodium salt PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 6.1 - 7.5
    		 76836-02-7 6.8
    • P1851 PIPES BioPerformance Certified, suitable for cell culture 6.1 - 7.5
    		 5625-37-6 6.8
    • P8203 PIPES BioXtra, ≥99% (titration) 6.1 - 7.5
    		 5625-37-6 6.8
    • P3405 POPSO hydrate ≥99% (titration) 7.2 - 8.5
    		 68189-43-5 (anhydrous) 7.8
    • P8907 POPSO sesquisodium salt ≥98% (titration) 7.2 - 8.5
    		 108321-08-0 7.8
    • T0647 TAPS sodium salt ≥99% (titration) 7.7 - 9.1
    		 91000-53-2 8.4
    • T5441 TAPS sodium salt BioPerformance Certified, suitable for cell culture, ≥99% 7.7 - 9.1
    		 91000-53-2 8.4
    • T5130 TAPS ≥99.5% (titration) 7.7 - 9.1
    		 29915-38-6 8.4
    • T5316 TAPS BioPerformance Certified, suitable for cell culture, ≥99.5% (titration) 7.7 - 9.1
    		 29915-38-6 8.4
    • T9659 TAPS BioXtra, ≥99.5% (titration) 7.7 - 9.1
    		 29915-38-6 8.4
    • T9269 TAPSO ≥99% (titration) 7.0 - 8.2
    		 68399-81-5 7.6
    • T1030 TES hemisodium salt 6.8 - 8.2
    		   7.5
    • T0772 TES sodium salt ≥99% (titration) 6.8 - 8.2
    		 70331-82-7 7.5
    • T1375 TES ≥99% (titration) 6.8 - 8.2
    		 7365-44-8 7.5
    • T5691 TES BioPerformance Certified, suitable for cell culture, ≥99% (titration) 6.8 - 8.2
    		 7365-44-8 7.5
    • T6541 TES BioXtra, ≥99.5% (titration) 6.8 - 8.2
    		 7365-44-8 7.5
    • 93318 TRIS buffered saline caplets (for 15 mL), pH 7.6      
    • RES3098T-B7 TRIS hydrochloride PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production., suitable for cell culture 7.0 - 9.0
    		 1185-53-1 8.1
    • T0377 Tricine ≥99% (titration) 7.4 - 8.8
    		 5704-04-1 8.1
    • T5816 Tricine BioPerformance Certified, suitable for cell culture, ≥99% (titration) 7.4 - 8.8
    		 5704-04-1 8.1
    • T9784 Tricine BioXtra, pH 4.0-6.0 (1 M in H2O), ≥99% (titration) 7.4 - 8.8
    		 5704-04-1 8.1
    • RES3077T-A7 Tricine PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture 7.4 - 8.8
    		 5704-04-1 8.1
    • TRIS-RO Tris base 7 - 9
    		 77-86-1 8.1
    • 93367 Trizma® Buffer substance for fish-farming, pH 8.3      
    • T8508 Trizma® Pre-Set Crystals Type 7.2-FT, pH 7.2, suitable for use with fresh water species      
    • T1753 Trizma® Pre-Set Crystals Type 7.4-FT, pH 7.4, suitable for use with fresh water species      
    • T1878 Trizma® Pre-Set crystals Type 8.3-FT, pH 8.3, suitable for use with marine species      
    • T7193 Trizma® Pre-set crystals BioPerformance Certified, pH 7.0, average Mw 154.8 7.0 - 9.0
    		    
    • T9943 Trizma® Pre-set crystals BioPerformance Certified, pH 7.0, average Mw 154.8 7.0 - 9.0
    		    
    • T7443 Trizma® Pre-set crystals BioPerformance Certified, pH 7.2, average Mw 153.8 7.0 - 9.0
    		    
    • T7693 Trizma® Pre-set crystals BioPerformance Certified, pH 7.4, average Mw 151.6 7.0 - 9.0
    		    
    • T0319 Trizma® Pre-set crystals BioPerformance Certified, pH 7.4, average Mw 151.6 7.0 - 9.0
    		    
    • T7818 Trizma® Pre-set crystals BioPerformance Certified, pH 7.5, average Mw 150.6 7.0 - 9.0
    		    
    • T7943 Trizma® Pre-set crystals BioPerformance Certified, pH 7.6, average Mw 149.0 7.0 - 9.0
    		    
    • T8068 Trizma® Pre-set crystals BioPerformance Certified, pH 7.7, average Mw 147.6 7.0 - 9.0
    		    
    • T8193 Trizma® Pre-set crystals BioPerformance Certified, pH 7.8, average Mw 145.8 7.0 - 9.0
    		    
    • T8443 Trizma® Pre-set crystals BioPerformance Certified, pH 8.0, average Mw 141.8 7.0 - 9.0
    		    
    • T0819 Trizma® Pre-set crystals BioPerformance Certified, pH 8.0, average Mw 141.8 7.0 - 9.0
    		    
    • T8568 Trizma® Pre-set crystals BioPerformance Certified, pH 8.1, average Mw 139.8 7.0 - 9.0
    		    
    • T8943 Trizma® Pre-set crystals BioPerformance Certified, pH 8.3, average Mw 135.4 7.0 - 9.0
    		    
    • T8818 Trizma® Pre-set crystals BioPerformance Certified, pH 8.5, average Mw 131.4 7.0 - 9.0
    		    
    • T1194 Trizma® Pre-set crystals BioPerformance Certified, pH 8.5, average Mw 131.4 7.0 - 9.0
    		    
    • T9443 Trizma® Pre-set crystals BioPerformance Certified, pH 8.8, average Mw 127.2 7.0 - 9.0
    		    
    • T9568 Trizma® Pre-set crystals BioPerformance Certified, pH 8.9, average Mw 125.6 7.0 - 9.0
    		    
    • T9693 Trizma® Pre-set crystals BioPerformance Certified, pH 9.0, average Mw 124.6 7.0 - 9.0
    		    
    • T9818 Trizma® Pre-set crystals BioPerformance Certified, pH 9.1, average Mw 123.0 7.0 - 9.0
    		    
    • T4661 Trizma® base ≥99.9% (titration), crystalline 7 - 9
    		 77-86-1 8.1
    • T6066 Trizma® base BioPerformance Certified, meets EP, USP testing specifications, suitable for cell culture, ≥99.9% (titration) 7 - 9
    		 77-86-1 8.1
    • T6791 Trizma® base BioXtra, pH 10.5-12.0 (1 M in H2O), ≥99.9% (titration) 7 - 9
    		 77-86-1 8.1
    • T1503 Trizma® base Primary Standard and Buffer, ≥99.9% (titration), crystalline 7 - 9
    		 77-86-1 8.1
    • 93350 Trizma® base puriss. p.a., ≥99.7% (T) 7 - 9
    		 77-86-1 8.1
    • T2944 Trizma® hydrochloride solution BioPerformance Certified, suitable for cell culture, pH 7.5 7.0 - 9.0
    		    
    • T1819 Trizma® hydrochloride solution pH 7.0, BioPerformance Certified, 1 M, suitable for cell culture 7.0 - 9.0
    		    
    • T2069 Trizma® hydrochloride solution pH 7.2, BioPerformance Certified, 1 M, suitable for cell culture 7.0 - 9.0
    		    
    • T2194 Trizma® hydrochloride solution pH 7.4, BioPerformance Certified, 1 M, suitable for cell culture 7.0 - 9.0
    		    
    • T2319 Trizma® hydrochloride solution pH 7.5, BioPerformance Certified, 1 M, suitable for cell culture 7.0 - 9.0
    		    
    • T2444 Trizma® hydrochloride solution pH 7.6, BioPerformance Certified, 1 M, suitable for cell culture 7.0 - 9.0
    		    
    • T2569 Trizma® hydrochloride solution pH 7.8, BioPerformance Certified, 1 M, suitable for cell culture 7.0 - 9.0
    		    
    • T2694 Trizma® hydrochloride solution pH 8.0, BioPerformance Certified, 1 M, suitable for cell culture 7.0 - 9.0
    		    
    • T3069 Trizma® hydrochloride solution pH 8.0, BioPerformance Certified, 2 M, suitable for cell culture 7.0 - 9.0
    		    
    • T2819 Trizma® hydrochloride solution pH 9.0, BioPerformance Certified, 1 M, suitable for cell culture 7.0 - 9.0
    		    
    • T5941 Trizma® hydrochloride BioPerformance Certified, suitable for cell culture, ≥99.0% (titration) 7.0 - 9.0
    		 1185-53-1 8.1
    • T6666 Trizma® hydrochloride BioXtra, pH 3.5-5.0 (0.5 M in H2O), ≥99.0% (titration) 7.0 - 9.0
    		 1185-53-1 8.1
    • T3253 Trizma® hydrochloride reagent grade, ≥99.0% (titration), crystalline 7.0 - 9.0
    		 1185-53-1 8.1
    • RES3193T-A7 Tromethamine PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture, Meets USP, EP, JPC, BP testing specifications.   77-86-1