New Products for Chemical Synthesis

Mass Spectrometry-Cleavable Crosslinkers
A suite of new sulfoxide-containing crosslinkers (909602,909610,909599,909688) are ideal tools for analysis of protein-protein interactions (PPIs). Each homobifunctional linker contains an amino acid-targeting reactive group, a spacer region, and two symmetrical C-S cleavable bonds that yield tagged peptides for unambiguous identification via collision-induced dissociation using tandem MS. Such linkers will find wide utility in the elucidation of PPIs, protein complex architecture, and structural dynamics.

FastWoRX Separation Technology
FastWoRX products are hydrophobic powders that absorb most organic compounds. With them, liquid-liquid extraction (LLE) for reaction workups can be replaced by a simple filtration or magnetic separation. Products are available for filtration (FASTWORX-S) or magnetic separation (FASTWORX-M).

Air-stable Ni Catalysis

Ni(COD)(DQ) (912794) is an air- and thermally stable Ni(0) precatalyst developed by the Engle lab at The Scripps Research Institute. This 18-electron complex has a unique stability profile allowing for easy reaction setup outside an inert atmosphere. Transformations such as the Suzuki-Miyaura coupling, borylation of aryl halides, and alkene hydroarylation have been demonstrated.

Synthetic Reagents

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915319 Aminosupersilane New
912395 NaBHT New
906719 Pyrylium tetrafluoroborate ≥95% New

Chemical Biology

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QBD10140 Acid-dPEG®25-NHS ester >95% (HPLC) New
910554 (S,R,S)-AHPC-PEG6-butyl CO2H ≥95% New
911801 AHPC-C6-PEG1-C3-PEG1-butyl amine hydrochloride ≥90% New
QBD10244 Amino-dPEG®4-acid >95% (HPLC) New
QBD10869 Amino-dPEG®36-OH >95% (HPLC) New
913863 Biotin-AEEA-tyramide New
QBD10193 Biotin-dPEG®3-NH3+TFA- >95% (HPLC) New
914479 Biotin-O2Oc-O2Oc-OH ≥95% New
914924 3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid ≥95% New
QBD10760 t-Boc-N-amido-dPEG®8-acid >95% (HPLC) New
QBD10761 t-Boc-N-amido-dPEG®12-acid >95% (HPLC) New
QBD10763 t-Boc-N-amido-dPEG®24-acid >95% (HPLC) New
QBD10902 t-Boc-N-amido-dPEG®36-acid >95% (HPLC) New
QBD11389 t-Boc-N-amido-dPEG®24-amido-dPEG®23-amine >95% (HPLC) New
QBD10093 t-Boc-N-amido-dPEG®23-amine >95% (HPLC) New
911755 C5 Lenalidomide-PEG5-NH2 hydrochloride New
911712 C5 Lenalidomine-C6-NH2 hydrochloride ≥95% New
911720 C5 Lenalidomine-C9-NH2 hydrochloride ≥95% New
909661 d0-DMDSSO crosslinker ≥95% New
913766 9,10-Dioxo-9,10-dihydrophenanthrene-3-carboxylic acid ≥95% New
QBD10909 m-dPEG®37-acid >95% (HPLC) New
QBD11094 m-dPEG®12-amido-dPEG®24-DSPE >95% (HPLC) New
QBD10908 m-dPEG®36-amine >95% (HPLC) New
QBD10918 m-dPEG®48-amine >95% (HPLC) New
QBD10199 dPEG®4-biotin acid >95% (HPLC) New
QBD10773 dPEG®24-biotin acid >95% (HPLC) New
QBD10776 dPEG®48-biotin acid >90% (HPLC) New
QBD11026 m-dPEG®24-DSPE >95% (HPLC) New
QBD10931 m-dPEG®36-MAL >95% (HPLC) New
QBD10932 m-dPEG®48-MAL >95% (HPLC) New
QBD10910 m-dPEG®37-NHS ester >95% (HPLC) New
QBD10728 m-dPEG®36-OH >90% (HPLC) New
QBD10792 m-dPEG®4-thiol >95% (HPLC) New
912417 Enantioprobe (S)-1 ≥95% New
912670 Enantioprobe (R)-2 ≥95% New
913170 Enantioprobe (S)-2 ≥95% New
912166 Enantioprobe (R)-3 ≥95% New
913405 Enantioprobe (S)-3 ≥95% New
912913 Enantioprobe (R)-4 New
913189 Enantioprobe (S)-4 ≥95% New
913162 Enantioprobe (R)-5 ≥95% New
912689 Enantioprobe (S)-5 ≥95% New
912425 Enantioprobe (R)-6 ≥95% New
912174 Enantioprobe (S)-6 ≥95% New
912921 Enantioprobe (R)-8 ≥95% New
913421 Enantioprobe (S)-8 ≥95% New
QBD10243 Fmoc-N-amido-dPEG®2-acid >95% (HPLC) New
QBD10273 Fmoc-N-amido-dPEG®8-acid >95% (HPLC) New
QBD10903 Fmoc-N-amido-dPEG®36-acid >95% (HPLC) New
914592 Fmoc-Cystamine HCl ≥95% New
914436 Fmoc-D-Lys(Biotin)-OH ≥95% New
QBD10613 Fmoc-N-Lys-(dPEG®4-biotin)-OH-(acid) >95% (HPLC) New
QBD10615 Fmoc-N-Lys-(dPEG®12-biotin)-OH-(acid) >95% (HPLC) New
914339 Fmoc-L-Lys(Nvoc)-OH ≥98% New
914231 4-(2-(Hex-5-ynamido)ethyl)benzenesulfonyl fluoride ≥95% New
QBD10722 Hydroxy-dPEG®24-t-butyl ester >90% (HPLC) New
Z744061 LightOx PhotoReact 365 New
QBD10644 Lipoamido-dPEG®36-TFP ester >90% (HPLC) New
QBD10275 MAL-dPEG®8-acid >95% (HPLC) New
QBD10416 MAL-dPEG®4-(m-dPEG4)3 >90% (HPLC) New
QBD11581 MAL-dPEG®4-Glu(TFP ester)-NH-m-dPEG®24 >90% (HPLC) New
QBD11471 MAL-dPEG®12-Tris(m-dPEG®24)3 >95% (HPLC) New
QBD11487 MAL-dPEG®24-Tris(-dPEG®24-Tris(m-dPEG®24)3)3 >95% (HPLC) New
QBD11597 MAL-[NH-dPEG®4-Glu(TFP ester)]3-NH-m-dPEG®24 >90% (HPLC) New
913839 2-Methylnicotinic acid imidazolide New
910066 6-(2-(2-(Oct-7-yn-1-yloxy)ethoxy)ethoxy)hexanoic acid ≥90% New
915572 Pomalidomide-dipiperazine-NH2 hydrochloride ≥95% New
911658 Pomalidomide-C3-NH2 hydrochloride ≥95% New
911666 Pomalidomide-C6-NH2 hydrochloride ≥95% New
913987 Pomalidomide-C6-PEG1-C3-PEG1-butyl amine hydrochloride ≥95% New
QBD10866 SPDP-dPEG®36-acid >95% (HPLC) New
QBD10867 SPDP-dPEG®36-NHS ester >95% (HPLC) New
QBD10247 Thiol-dPEG®4-acid >95% (HPLC) New
QBD10850 Thiol-dPEG®12-acid >95% (HPLC) New
914746 Thiophosphoro alkyne dichloridate ≥95% New
914983 ThT-NE ≥95% New

Catalysis

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915378 AdBrettPhos Pd G6 Br New
915602 AlPhos Pd G6 Br New
913456 (R)-AntPhos ≥97% New
912476 (S)-AntPhos ≥97% New
912964 (R,R)-BABIBOP ≥97% New
913219 (S,S)-BABIBOP New
913200 (R)-BIDIME ≥97% New
918008 GPhos ≥95% New
916064 cis-Hexamethylphosphetane oxide ≥95% New
912727 (2R,3R)-iPr-BIDIME New
903698 1-Isopropyl-4-methyl-5-norbornene New
912956 (2R,2′R,3R,3′R)-MeO-BIBOP New
912972 (2S,2′S,3S,3′S)-MeO-BIBOP ≥97% New
915610 PrPPTNO ≥95% New
913227 (2R,2R′,3R,3R′)-WingPhos New
913472 (2S,2S′,3S,3S′)-WingPhos ≥95% New