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U9257 Sigma-Aldrich

UbcH9 Conjugating Enzyme human

≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution

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Description

General description

Manufactured for Sigma by Boston Biochem., Inc.

Biochem/physiol Actions

UbcH9 mediates the conjugation of SUMO-1, SUMO-2, and SUMO-3 to a diverse variety of proteins without the help of an E3 ligase. This E2 conjugating enzyme interacts directly with protein substrates that are modified by SUMOylation, and may help in substrate recognition. UbcH9 is specific for the conjugation of proteins modified by SUMOylation.

Physical form

Solution in 50 mM HEPES, pH 7.5, 100 mM NaCl, 10 % glycerol, 1mM TCEP.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles
Peer-Reviewed Papers
15

References

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