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U8632 Sigma-Aldrich

Ubiquitin-Carrier Protein H5a, GST-tagged human

≥95% (SDS-PAGE), liquid

Synonym: UbcH5a human

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Properties

Related Categories Application Index, Biochemicals and Reagents, Cell Signaling Enzymes, Cell Stress and Refolding, Enzymes, Inhibitors, and Substrates,
recombinant   expressed in E. coli
assay   ≥95% (SDS-PAGE)
form   liquid
mol wt   47 kDa
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... UBE2D1(7321), UBE2N(7334)

Description

General description

Manufactured for Sigma by Boston Biochem., Inc.

Biochem/physiol Actions

Human homologs of the yeast UBC4/5 family and play many important regulatory roles in inflammation and cancer.

Mediates the degradation of a myriad of short-lived regulatory proteins including the tumor suppressor p53 in the presence of E6/E6-AP or MDM2, the c-Fos transcription factor, and the signal-induced ubiquitination of IκBα, UBC5 is an essential gene in yeast.

Physical form

Solution in 50 mM HEPES, pH 8.0, 100 mM NaCl, 1 mM DTT in 10% glycerol.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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