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H9776 Sigma-Aldrich

Heat Shock Protein 70 from bovine brain

>95% (SDS-PAGE), lyophilized powder

Synonym: HSP 70

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Properties

Related Categories Application Index, Biochemicals and Reagents, Cell Biology, Cell Culture, Cell Signaling Enzymes,
biological source   bovine brain
assay   >95% (SDS-PAGE)
form   lyophilized powder
composition   Protein, ~10% Lowry
application(s)   western blot: suitable
storage temp.   −20°C
Gene Information   bovine ... HSPA1A(282254), HSPA8(281831)

Description

Application

Heat shock protein 70 (Hsp70) from bovine brain has been used as a protein standard in Western blotting to check levels of the Hsp70 family proteins in honey bees after heat exposure. It has been used as a standard for the quantification of HSP70, obtained from liver sections of rats, by ELISA (enzme-linked immunosorbent assay).

Packaging

0.2 mg in serum bottle

Biochem/physiol Actions

HSPs (heat shock proteins) are needed for protein folding, protein assembly, protein aggregation and protein transport. They help in maintaining cellular homeostasis and offer cytoprotective effects. Hsp70 is associated with the protective effects on rat myocardial cells in presence of heat stress. Similarly, it offers neuro-protection from oxygen-glucose deprivation injury.

Physical form

Contains Tris buffer salts.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

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Peer-Reviewed Papers
15

References

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