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1.08382 Millipore

Tris(hydroxymethyl)aminomethane

GR for analysis buffer substance ACS,Reag. Ph Eur

Synonym: 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol

  • CAS Number 77-86-1

  • Linear Formula NH2C(CH2OH)3

  • Molecular Weight 121.14

  •  Beilstein/REAXYS Number 741883

  •  MDL number MFCD00004679

  •  EC Index Number 201-064-4

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Properties

Quality Level   400
grade   ACS reagent
Agency/Method   reag. Ph. Eur.
vapor pressure   0.0267 hPa ( 20 °C)
potency   >5000 mg/kg LD50, oral (Rat)
  >5000 mg/kg LD50, skin (Rat)
pH   10.2-10.6 (20 °C, 6 g/L in H2O)
useful pH range   7 - 9
pKa (25 °C)   8.1
bp   219-220 °C/10 mmHg (lit.)
  219-220 °C/13.3 hPa
mp   167-172 °C (lit.)
solubility   678 g/L
density   1.35 g/cm3 at 23 °C
bulk density   840 kg/m3
SMILES string   NC(CO)(CO)CO
InChI   1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
InChI key   LENZDBCJOHFCAS-UHFFFAOYSA-N
storage conditions   Store at +15°C to +25°C.

Description

General description

Biological buffer substance
Tris is widely used as a biological buffer substance in the pH range of 7-9. For example it is used for the freezing of proteins. The grade conforms precisely with the Reag. Ph. Eur. requirements.

GR for analysis buffer substance ACS,Reag. Ph Eur

Application

Tris(hydroxymethyl)aminomethane GR for analysis buffer substance ACS,Reag. Ph Eur. CAS 77-86-1, EC 201-064-4, chemical formula H₂NC(CH₂OH)₃.

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Safety Information

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