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nitric oxide synthase trafficking
Synonyms DaIP2
Species Human (115677) , Species Mouse (329416) , Species Rat (311111) , Species Zebrafish (100148449) , Species cow (521834) , Species domestic cat (101084813) , Species dog (478780) , Species naked mole-rat (101713879) , Species domestic guinea pig (100714437) , Species sheep (101122001)
Summary: Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM, Apr 2004]